Resealed Erythrocytes: A Novel Carrier for Drug Targeting
نویسندگان
چکیده
Erythrocytes, also known as red blood cells, and have been extensively studied for their potential carrier capabilities for the delivery of drugs. Such drug-loaded carrier erythrocytes are prepared simply by collecting blood samples from the organism of interest, separating erythrocytes from plasma, entrapping drug in the erythrocytes, and resealing the resultant cellular carriers, these carriers are called resealed erythrocytes. An attempt has been made to make a review on the fabrication, in vitro characterization and biomedical application of Resealed erythrocytes. Key word: Resealed erythrocytes, Novel carrier, Drug targeting. _____________________________________________________________________________
منابع مشابه
Resealed Erythrocytes: Potential Carrier for Delivery of Drugs
S. K. Shyama*, K. S. Rathore, Roshan Keshri B. N. Institute of Pharmaceutical Sciences, Udaipur Rajasthan 313001 Erythrocytes, also known as red blood cells, have been extensively studied for their potential carrier capabilities for the delivery of drugs and drug-loaded microspheres. Such drug-loaded erythrocytes are prepared simply by collecting blood samples from the organism of interest, sep...
متن کاملMechanism of Drug Loading, Evaluation and Applications of Erythrocytes as Carriers for Drug Targetting
Resealed Erythrocytes are of appropriate size and shape to carry drugs. They are biocompatible and they have minimum toxic side effects. Minimum leakage can be observed before they reach the target site and they are able to carry broad spectrum of drugs. Carrier erythrocytes and resealed erythrocytes are being used for continuous implementation of safe and effective delivery of various drugs fo...
متن کاملResealed Erythrocytes as a Potential Drug Carrier System
Novel drug delivery system has been introduced to overwhelm the drawback of fluctuating drug levels associated with conventional dosage forms. Out of various cellular carrier systems, erythrocytes (red blood cells, RBC) have been the most widely investigated and found to possess great potential for the delivery of drugs and drug-loaded microspheres. These cellular carriers, having remarkable bi...
متن کاملResealed Erythrocytes - As a Carrier
Amongst various carriers explored for target oriented drug delivery, vesicular, microparticulate and cellular carriers meet several criteria rendering them useful in clinical applications. Lymphocytes, leukocytes, platelets, granulocytes and erythrocytes have been proposed as a cellular carrier. Erythrocytes, also known as red blood cells, and have been the most extensively investigated and fou...
متن کاملA Sure Shot Potential Drug Carrier Option with Multi Aspects- Resealed Erythrocytes
Based on the global product revenue there is a drug delivery product with 15% of annual growth rate, annual income of approximately US$43 billion and biodegradable, biocompatible like properties is none other than resealed erythrocytes. It has the capability of reaching the target with minimal side effects which make its demand in the research field to do more and more. Under the shadow of thes...
متن کامل